Spinal Disease

Cervical Spinal Disease

Change in Functional Status Following Cervical Decompression With Fusion for Cervical Disc Herniation

Surgical Dates: January 2, 2019 – December 26, 2019

PHQ-9 = Patient Health Questionnaire, PROMIS = Patient-Reported Outcomes Measurement Information System

In patients who underwent cervical decompression with fusion for symptoms of severe arm pain due to a cervical disc herniation, median duration of follow-up after surgery was 140 days. Among patients assessed using the Patient-Reported Outcomes Measurement Information System (PROMIS®), 43% noted clinically meaningful improvement of their Physical quality of life scores and 44.4% noted clinically meaningful improvement in their Mental scores. In this and subsequent graphs, clinically meaningful change in PROMIS scores was defined as a change of one-half of a standard deviation.¹ Among 141 patients reporting at least moderate depressive symptoms, defined as Patient Health Questionnaire (PHQ-9) score ≥ 10, at baseline, 17.7% noted clinically meaningful improvement in depressive symptoms and 70.2% were stable. Improvement in PHQ-9 was defined as a change of ≥ 5 points.²

Change in Functional Status Following Cervical Decompression Without Fusion for Cervical Disc Herniation

Surgical Dates: January 2, 2019 – November 19, 2019

PHQ-9 = Patient Health Questionnaire, PROMIS = Patient-Reported Outcomes Measurement Information System

In patients who underwent cervical decompression without fusion for symptoms of severe arm pain due to a cervical disc herniation, median duration of follow-up after surgery was 138 days. Among patients assessed using PROMIS, 39.6% noted clinically meaningful improvement of their Physical quality of life scores and 37.5% noted clinically meaningful improvement in their Mental scores. Among 25 patients reporting at least moderate depressive symptoms (PHQ-9 ≥ 10) at baseline, 12% noted clinically meaningful improvement in depressive symptoms and 60% were stable.

References
  1. Norman GR, Sloan JA, Wyrwich KW. Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. Med Care. 2003 May;41(5):582-592.
  2. Löwe B, Unützer J, Callahan CM, Perkins AJ, Kroenke K. Monitoring depression treatment outcomes with the Patient Health Questionnaire-9. Med Care. 2004 Dec;42(12):1194-1201.