Neurological Institute Outcomes

In patients who underwent cervical decompression with fusion for symptoms of severe arm pain due to a cervical disc herniation, median duration of follow-up after surgery was 140 days. Among patients assessed using the Patient-Reported Outcomes Measurement Information System (PROMIS®), 43% noted clinically meaningful improvement of their Physical quality of life scores and 44.4% noted clinically meaningful improvement in their Mental scores. In this and subsequent graphs, clinically meaningful change in PROMIS scores was defined as a change of one-half of a standard deviation.¹ Among 141 patients reporting at least moderate depressive symptoms, defined as Patient Health Questionnaire (PHQ-9) score ≥ 10, at baseline, 17.7% noted clinically meaningful improvement in depressive symptoms and 70.2% were stable. Improvement in PHQ-9 was defined as a change of ≥ 5 points.²

In patients who underwent cervical decompression without fusion for symptoms of severe arm pain due to a cervical disc herniation, median duration of follow-up after surgery was 138 days. Among patients assessed using PROMIS, 39.6% noted clinically meaningful improvement of their Physical quality of life scores and 37.5% noted clinically meaningful improvement in their Mental scores. Among 25 patients reporting at least moderate depressive symptoms (PHQ-9 ≥ 10) at baseline, 12% noted clinically meaningful improvement in depressive symptoms and 60% were stable.