Dermatology & Plastic Surgery Institute Outcomes
Characterizing Malignant Melanomas Co-Occurring With Seborrheic Keratosis
Seborrheic keratoses (SK) are colloquially known as “wisdom spots” due to their frequent occurrence among older patients; however their prevalence among younger patients is rising.¹⁻² Typically they are described as flesh-colored to dark brown, verrucous, “stuck-on” papules with pseudohorn cysts evident on dermatoscopy. SKs are usually dismissed as benign and usually removed for cosmetic reasons; however sometimes malignant transformation into melanoma, may occur.³⁻⁴
Institute physicians saw 14 cases of MM arising in SK (MMaSK) and 10 cases of MM merging with SK (MMmSK) from 2012–2017. Demographic data were compared to a SK control group matched on age, sex, and site of lesion during the same time.
Melanoma arising in MMaSK is described as a co-occurrence of MM and SK characteristics in the same lesion (N = 14). MMmSK was identified if there were two separate lesions colliding (N = 10).