As might be surmised by the preceding description of the factors causing or influencing ISD, diagnosis consists of a comprehensive psychological examination and perhaps a limited physical exam. The endeavor is to identify or eliminate all factors involved in the problem and assign each a weight or value so that they can be dealt with appropriately
Some diagnoses are simple such as determining that the disorder stems from the side effects of a particular medication. Others are more complex. When depression is associated with ISD, the sexual specialist must then determine the role depression is playing. Did it lead to ISD or did the disorder lead to depression? Laboratory tests may be conducted to determine hormone levels.