Darlene A. Lobel, MD, is a Staff Neurosurgeon in the Center for Neurological Restoration in the Neurological Institute and an Associate Professor of Surgery at the Cleveland Clinic Lerner College of Medicine. Dr. Lobel performs Deep Brain Stimulation (DBS) surgery for patients with Parkinson's Disease, tremor, dystonia, and psychiatric disorders, as well as procedures for patients with intractable pain syndromes and spasticity. She also performs stereotactic biopsy and resection of brain tumors as well as gamma knife radiosurgery for tumors and movement disorders. She holds joint appointments in the Department of Biomedical Engineering and in the Gamma Knife Center.
Dr. Lobel received her Bachelor of Science degree from Duke University and her Medical Doctorate from the Medical College of Georgia in 2000. She completed her residency in neurological surgery at MCG in 2006. She then pursued fellowship training in stereotactic neurosurgery and radiosurgery at UCLA, and further training in functional neurosurgery and epilepsy surgery at Emory University, completing her fellowship there in 2007. She held academic positions at both UCLA and Emory during her fellowship training, dedicating her time to educating residents and other clinicians.
Dr. Lobel was recruited to the University of Florida-Jacksonville in 2007 as an Assistant Professor of Neurosurgery, where she built up a busy subspecialty practice in deep brain stimulation and spinal cord stimulation. In 2009, she was recruited to a practice in Georgia, where she served as Chief of Neurosurgery for her private practice group until 2011.
In 2011, Dr. Lobel was invited to work in Grenoble, France with Dr. Alim-Louis Benabid, the founder of modern day Deep Brain Stimulation (DBS) for treatment of Parkinson's Disease. During the 18 months working with Dr. Benabid, Dr. Lobel enhanced her knowledge of DBS, while also working on the development of a Brain Computer Interface (BCI) system for patients with traumatic spinal cord injury. At Clinatec, a biomedical translational research facility in Grenoble, Dr. Lobel worked closely with a multi-disciplinary team of engineers, technicians, mathematicians, informaticians, biologists, and other medical doctors on the design and implementation of the BCI system conceived by Dr. Benabid. She developed a passion for this research during her tenure in France, and now continues to conduct research in BCI systems at Cleveland Clinic.
Dr. Lobel was recruited to Mayo Clinic while she was working in France, to serve as a liaison between Clinatec and Mayo Clinic in the development of a clinical research protocol involving both centers. In addition to facilitating this research collaboration, Dr. Lobel was integrally involving in a preclinical research trial using intraspinal microstimulation (ISMS) to reanimate paralyzed limbs. She contributed to the ISMS system design, and served as a neurosurgeon for the trial. She also served as advisor for PhD candidates and medical students in the lab. In addition to her research contributions, she was involved clinically in the Department of Neurologic Surgery at Mayo, participating in DBS patient management conferences and educating neurosurgery residents through lectures and grand rounds presentations.
In addition to pursuing her clinical interests, Dr. Lobel has dedicated her time to resident education, developing the first neurosurgical course at UF-Jacksonville for residents using simulation based training techniques. She has served as faculty and course director for educational courses at the AANS and CNS national meetings. One of her greatest contributions to neurosurgical education is her integral role in the development of the Congress of Neurological Surgeons Resident Training Program in Neurosurgical Simulation, created in 2010. She continues to serve as Co-director for CNS sponsored resident simulation courses today.
Dr. Lobel has demonstrated her dedication to clinical expertise, research pursuits, and education. She has made major contributions to the medical and biomedical communities. Dr. Lobel is an internationally acclaimed speaker. She has served as Co-Investigator and Consultant in clinical trials in the US and in France and has authored several publications, including peer-reviewed manuscripts and book chapters. Her expertise is widely sought after as a reviewer, invited speaker, and as an expert by other scientists and researchers.