Research & Publications †
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My research has focused on the development of novel optical imaging systems by leveraging technologies in engineering and biomedical sciences to create multimodal imaging tools for the clinical diagnosis and treatment monitoring of pathologies in ophthalmology, gastroenterology, and oncology. Optical imaging techniques are particularly attractive for visualizing tissue morphology, biological dynamics, and disease pathogenesis because they allow for noninvasive access to subcellular-resolution diagnostic information. Optical coherence tomography is a novel imaging modality that allows for fast, noncontact, high-resolution volumetric imaging of weakly scattering tissue. Nonlinear microscopy has advantages of high resolution, molecular-specificity, and improved imaging depth and contrast over conventional white-light and fluorescence microscopes, enabling endogenous and exogenous contrast imaging in both in vivo and ex vivo specimens. Finally, functional optical imaging techniques, such as spectroscopy and Doppler velocimetry, enhance optical contrast by detecting properties of tissues, such as oxygenation and blood flow, that are correlated with cellular metabolism and early indicators of disease.
Biomedical optics, Optical coherence tomography, Ophthalmology Oncology
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As of 9/1/2014, Dr. Tao has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.
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