Richard Ransohoff, M.D.

Director, Center for Neuroinflammation Research

Richard M. Ransohoff, MD, is Director of the Neuroinflammation Research Center in the Department of Neurosciences of Lerner Research Institute, Cleveland Clinic; Professor of Molecular Medicine at the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University; and Staff Neurologist in the Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, Ohio. Dr. Ransohoff graduated with honors from Bard College, Annandale, N.Y., with a BA in literature, and received an MD degree with honors from Case Western Reserve University School of Medicine. He completed residencies in internal medicine at Mt. Sinai Medical Center in Cleveland (board-certified, 1981) and in neurology at Cleveland Clinic (board-certified, 1985). From 1984 until 1989, Dr. Ransohoff was a Postdoctoral Fellow in the laboratory of Dr. Timothy Nilsen in the Department of Molecular Biology and Microbiology at Case Western Reserve University School of Medicine.

Among other honors and awards, Dr. Ransohoff received a Physician’s Research Training Award from the American Cancer Society (1984-1986); a Harry Weaver Neuroscience Scholarship from the National Multiple Sclerosis Society (NMSS; 1987-1992); a Clinical Investigator Development Award from the National Institutes of Health (NIH; 1988-1993); and the John and Samuel Bard Award in Science and Medicine (2002). He has been cited from 1996 through 2007 in the “Best Doctors in America” for his expertise in the clinical care of patients with multiple sclerosis (MS). Dr. Ransohoff was elected to the American Association of Physicians in 2006. He received the Cleveland Clinic Lerner Research Institute’s Award for Excellence in Science in 2006. Dr. Ransohoff was elected a Fellow of the American Association for the Advancement of Science in 2007.

Dr. Ransohoff served as regular member on study sections of the NIH and NMSS (as Chair). He has served on the Editorial Boards of the Journal of Immunology (2002-2005 as Section Editor), Trends in Immunology, the Journal of Neuroimmunology, Nature Reviews Immunology, and Neurology (Associate Editor). From 1998-2000, Dr. Ransohoff was a member of the NINDS Director's Planning Panel on “The Neural Environment.” He is a member of the Steering Committee for the NIH Therapeutic Development Program in Spinal Muscular Atrophy; the International Advisory Boards for the 7^th (2004) and 8^th (2006) Congresses on Neuroimmunology; and the Scientific Advisory Board for Chemocentryx, Mountain View, Calif. He serves on External Advisory Boards for CHARTER (CNS HIV Anti-Retroviral Therapy Effects Research; MH22005); a Program Project on Alexander’s Disease (NS 42803); the MS Lesion Project (NMSS RG 3185); the University of Nebraska’s Center for Neurovirology and Neurodegenerative Disorders (NS43985) and was the External Advisor for the European Union’s Project on "Mechanisms of Brain Inflammation” (QLG3-00612). He is a member of the National MS Society’s Medical Advisory Board. He is the Co-Director of the Marine Biological Laboratory’s special topics course on “Pathogenesis of Neuroimmunologic Disease” held biennially at Wood’s Hole, Mass. He is a member of the External Advisory Board for Meharry Medical College’s Special Neuroscience Research Program.

For the past decade, Dr. Ransohoff’s research has focused on the functions of chemokines and chemokine receptors in development and pathology of the nervous system. He also has a longstanding and continuing interest in the mechanisms of action of interferon-beta. Dr. Ransohoff has received research support from the NIH and the NMSS continuously for 20 years. He has published more than 150 scientific reports, more than 50 reviews and book chapters, and edited three books.

Dr. Ransohoff is a member of the American Academy of Neurology, the American Neurological Association, and the American Association of Physicians and is a Fellow of the American Association for the Advancement of Science.

Dr. Ransohoff is married to Margaret Seidler Ransohoff. They have two daughters, Amy Julia and Lena Jane.

• Lists more than 230 publications in PubMed as of January 2008

• Postdoctoral Fellow, Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, 1984-1988

Neurology

Internal Medicine

• U.S. Patent No. 6,414,118: beta-R1 chemokine
• U.S. Patent No. 5,977,334: DNA encoding beta-R1 chemokine comprising the beta-R1 promoter

• Best Doctors, for expertise in care of patients with multiple sclerosis, Since 1996
• Fellow, American Association for the Advancement of Science
• Chair, Peer Review Committee B, National Multiple Sclerosis Society, Since 2003
• Co-Director, Marine Biological Labs Special Topics Course, "Pathogenesis of Neuroimmunologic Disease," Since 2004
• Associate Editor, Neurology, Since 2006
• Member, Editorial Advisory Board, Trends in Immunology
• Member, Editorial Advisory Board, Nature Immunology Reviews
• ANA/John Whitaker Visiting Professor, University of California/Irvine, 2008

• American Academy of Neurology
• American Neurological Association
• Fellow, American Association for the Advancement of Science, 2007
• Association of American Physicians

• ChemoCentryx, Inc.
• Vertex Pharmaceuticals Incorporated

• ChemoCentryx, Inc.