Richard Rudick, M.D.

Director, Mellen Center

Vice Chair, Research

Richard A. Rudick, MD, is currently Professor of Medicine in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, the Hazel Prior Hostetler Chair of Neurology, Director of the Mellen Center for Multiple Sclerosis Treatment and Research, and Vice Chairman of Research and Development in the Neurological Institute at Cleveland Clinic.

Dr. Rudick graduated from Case Western Reserve University School of Medicine in 1975. Following internship and residency in medicine at the University of Connecticut, Dr. Rudick trained in neurology at the University of Rochester. During a postdoctoral research fellowship in the Center for Brain Research at the University of Rochester, studies focused on neurologic consequences of immune complex disease in animal systems and immunologic abnormalities in multiple sclerosis (MS) patients. Dr. Rudick’s subsequent studies on cerebrospinal fluid in MS were supported by an NIH clinical investigator career development award.

Dr. Rudick became Director of the Mellen Center in 1987. He has played key roles in several MS clinical trials, including pivotal registration trials of IFNß-1a (Avonex) and natalizumab (Tysabri) for relapsing-remitting MS. He continues studies on immunologic changes in MS patients, has led development of new clinical and imaging measures for MS trials and maintains a consultative clinical practice at the Mellen Center. Dr. Rudick has maintained continuous competitive grant funding from the NIH and the National Multiple Sclerosis Society for over 25 years.

Dr. Rudick established the Office of Clinical Research at Cleveland Clinic in 2001, and was the founding Chairman of the Division of Clinical Research in 2003. In that role, Dr. Rudick established a new General Clinical Research Center at Cleveland Clinic, secured a large Roadmap Clinical Research Training Program award from NIH (the Roadmap K12 Program), led a multidisciplinary effort to secure accreditation of the Cleveland Clinic Human Subjects Protection Program, and provided oversight for expansion of patient-based clinical and translational research. Dr. Rudick played a pivotal role in securing a Clinical and Translational Sciences Award from the NIH, serving as the CTSA Co-Principal Investigator. The CWRU/Cleveland Clinic CTSA created an academic home for clinical and translational research and city-wide infrastructure to support patient-based research.

• Vice Chairman, Researchand Development, Neurological Institute, 2007-Present
• Director, Mellen Center for Multiple Sclerosis Treatment and Research, and Hazel Prior Hostetler Professor of Neurology, 1987-Present
• Chairman, Division of Clinical Research, Cleveland Clinic, 2003-2007
• Co-Principal Investigator, Case Western Reserve University/Cleveland Clinic CTSA, 2000-Present
• Principal Investigator, Cleveland Multidisciplinary Clinical Research Training Program (Roadmap K12 Program), 2004-Present

Neurology

Internal Medicine

• Alpha Omega Alpha Honorary Medical Society, elected as a Junior Student, Case Western Reserve University School of Medicine, 1974
• Outstanding Alumnus of the Year Award, Ohio University College of Arts and Sciences, 1994
• Bruce Hubbard Stewart Award for Humanistic Medicine, Cleveland Clinic, 1995
• Hazel Prior Hostetler Professor of Neurology, Cleveland Clinic, 1996
• Alumnus of the Year Award, Department of Neurology, University of Rochester, 1998
• Innovation Award for Brain Parenchymal Fraction Software, Enterprise Development, Inc., 2000
• Arnold and Geri King Lifetime Achievement Award, National Multiple Sclerosis Society, 2002
• Health Care Professional Hall of Fame Award, National Multiple Sclerosis Society, 2003
• Continuously funded by the National Institutes of Health (NINDS, NCRR) and the National MS Society, 1981-Present
• National Center for Research Resources (NIH) Council, 2006-Present
• Council of Councils Member (NIH Director's Office), 2007-Present

• American Academy of Neurology
• American Neurological Association
• American Association for the Advancement of Science (Fellow)
• American Association of Physicians
• Alpha Omega Alpha Honorary Medical Society

• Biogen Idec