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Selected Publications

Facial Plastic & Reconstructive Surgery
  1. Novel tyramine linked hyaluronic acid (HA) derivatives in facial soft tissue reconstruction

    Collaborator: Anthony Calabro, PhD, Dept of BME. CCF Lerner Institute

    Current research is ongoing on the use of cross-linked HA as a long tern soft tissue replacement. This is presently funded by an RPC grant (# 7550, P.I. Daniel S. Alam, MD). Based on preliminary in vitro and in vivo data, the findings of this project could represent a new paradigm in soft tissue reconstruction. We have submitted for a resident research award for long-term study and funding for our research resident who plans to dedicate his research year to this project. The initial data has been received with enormous interest from our national academy which published the abstract not only at the national meeting but because of it’s potential merit, included it into a newsletter sent to all of the members of the society of facial plastic surgeons nationally.

  2. Three-dimensional flow analysis of the nasal valve based on fine cut CT data.

    Collaborator: Marc Goodin, PhD, Dept of BME. CCF Lerner Institute.

    With the utilization of flow dynamics models used presently in cardiology to study vessel flow, the section is pursuing the development of a model of flow limitation in nasal respiration. This will allow preoperative CT scans to predict and guide surgery for the improvement of nasal breathing. Compilation of data from presently existing CT scans from sinus patients has allowed the construction of a preliminary model.

  3. Novel surgical techniques

    Application of novel techniques to longstanding surgical problems in facial plastic surgery:

    • TMJ reconstruction in patients with composite reconstructions of the jaw: First reported use of alloderm based TMJ reconstruction with a fibula free flap bony construct.
    • Midfacial Suspension for patients with long standing facial paralysis: Use of a minimally invasive novel suture suspension technique to rehabilitate patients with long standing facial paralysis and facial droop.
    • Intranasal microplating for correction of cartilaginous nasal deformities: Novel approach to the management of posttraumatic nasal deformities
    • Serratus/Rib free flap reconstruction of head and neck defects: largest clinical series and report of the long term success of this flap in head and neck reconstruction
Nasal & Sinus Disorders

In Press

Cannady SB, Batra PS, Sautter NB, Roh HJ, Citardi, MJ. "New staging system for sinonasal inverted papilloma in the endoscopic era." Laryngoscope. In press.

Chung BJ, Batra PS, Citardi MJ, Lanza DC. "Endoscopic septoplasty: revisitation of the technique, indications, and outcomes." American Journal of Rhinology. In press.

Sautter N, Batra PS, Roh HJ, Citardi MJ. "Comparison of Open vs. endoscopic resection of inverted papilloma." American Journal of Rhinology. In press.

Solares CA, Citardi MJ, Batra PS. "Management of frontal sinus mucoceles with posterior table erosion in pre-transplant cystic fibrosis patients." American Journal of Otolaryngology. In press.

2006 Peer-reviewed Publications

Batra PS, Lanza DC. "Endoscopic power-assisted orbital exenteration." Skull Base 2006; 16 (Suppl 1):17.

Batra PS, Shipchandler TZ, Citardi MJ, Lanza DC. "Outcomes for endoscopic resection of sinonasal squamous cell carcinoma." Skull Base: An Interdisciplinary Approach. 2006; 16: S1-2.

Cho JH, Citardi MJ, Lee WT, Sautter NB, Lee HM, Yoon JH, Hong SC, Kim JK. "Comparison of frontal pneumatization patterns between Koreans and Caucasians." Otolaryngology-Head and Neck Surgery. 2006; 135, 780-786.

Citardi MJ , Batra PS. "Reconstruction of the skull base defects after minimally invasive endoscopic resection of anterior skull base neoplasms." Skull Base: An Interdisciplinary Approach. 2006; 16: S23.

Citardi MJ , Batra PS. "Imaging of the internal carotid artery and adjacent skull base with three-dimensional CT angiography for preoperative planning and intraoperative surgical navigation." Skull Base: An Interdisciplinary Approach. 2006; 16: S30.

Citardi MJ, Song W, Batra PS, Lanza DC, Hazen SL. "Characterization of oxidative pathways in chronic rhinosinusitis and sinonasal polyposis." American Journal of Rhinology. 2006; 20:353-359.

Knott PD, Batra PS Citardi MJ. "Contour-based & paired-point registration in a model for image-guided surgery." Laryngoscope. 2006; 116:1877-1881.

Leong JL, , Batra PS, Citardi MJ. "CT-MR image fusion for the management of skull base lesions." Otolaryngology-Head and Neck Surgery. 2006; 134:868-576.

Leong JL, Citardi MJ, Batra PS. "Reconstruction of skull base defects after minimally invasive endoscopic resection of the anterior skull base neoplasms." American Journal of Rhinology. 2006; 20:476-482.

Rizzi M, Batra PS, Prayson R, Citardi MJ. "Nasal histoplasmosis: report of a case." Otolaryngology-Head and Neck Surgery. 2006; 135:803-804.

Solares CA, Batra PS, Hall GS, Citardi MJ. "Treatment of chronic rhinosinusitis exacerbations due to methicillin-resistant Staphylococcus aureus with mupirocin irrigations." American Journal of Otolaryngology. 2006; 27:161-165.

2006 Publications (Other)

Batra PS. "The role of endoscopy in the allergist’s office." Curr Allergy Asthma Rep 2006; 6:228-31.

Batra PS, Citardi MJ. "Malignant sinonasal neoplasms." Otolaryngologic Clinics of North America. 2006; 39:619-637.

Citardi MJ , Batra PS. "CT-MR fusion for the management of skull base lesions." Skull Base: An Interdisciplinary Approach. 2006; 16:S30.

Citardi MJ, Batra PS (eds.). "Advanced techniques in rhinology." Otolaryngologic Clinics of North America. 2006; vol. 39.

Citardi MJ, Batra PS. "Advanced techniques in rhinology." Otolaryngologic Clinics of North America. 2006; 39: xiii-xiv.

Knott PD, Batra PS, Citardi MJ. "Computer-aided surgery." Otolaryngologic Clinics of North America. 2006; 39:203-522.

2005 Peer-Reviewed Publications

Batra PS, Citardi MJ, Lanza DC. "Combined endoscopic trephination and endoscopic frontal sinusotomy for the management of complex frontal sinus pathology." American Journal of Rhinology. 2005; 19:435-441.

Batra PS, Citardi MJ, Worley S, Lee J, Lanza DC. "Resection of anterior skull base tumors: comparison of combined traditional and endoscopic approaches." American Journal of Rhinology. 2005; 19:521-528.

Batra PS, Citardi MJ, Lanza DC. "Isolated sphenoid sinusitis after pituitary surgery." American Journal of Rhinology. 2005; 19:185-189.

Cannady SB, Batra PS, Citardi MJ, Lanza DC. "Comparison of delivery of topical medications to the paranasal sinuses via “vertex-to-floor” position and atomizer spray after FESS." Otolaryngology-Head & Neck Surgery. 2005; 133:735-740.

Fakhri S, Citardi MJ, Wolfe S, Batra PS, Lanza DC. "Challenges in the management of sphenoid inverted papilloma." American Journal of Rhinology. 2005; 19:207-213.

Friedman AD, Batra PS, Fakhri S, Citardi MJ, Lanza DC. "Isolated sphenoid sinus disease: etiology and management." Otolaryngology-Head & Neck Surgery. 2005; 133:544-550.

Leong JL, Batra PS, Citardi MJ. "Imaging of the internal carotid artery and adjacent skull base with three-dimensional CT angiography for preoperative planning and intraoperative surgical navigation." Laryngoscope. 2005; 115:1618-1623.

Shipchandler TZ, Batra PS, Citardi MJ, Bolger WE, Lanza DC. "Outcomes for endoscopic resection of sinonasal squamous cell carcinoma." Laryngoscope. 2005; 115:1983-1987

Rizzi M, Batra PS, Citardi MJ, Lanza DC. "An assessment of the presence of bacterial contamination of Venturi principle atomizers in a clinical setting." American Journal of Rhinology. 2005; 19: 21-24.

Scharpf J, Dean R, Stultz T, Citardi MJ. "The magnetic resonance imaging profile of occult intracranial violations due to sinus surgery." American Journal of Otolaryngology. 2005; 26:411-414.

2005 Publications (Other)

Citardi, MJ, Batra PS. "Image-Guided Sinus Surgery: Current Concepts & Technology." Otolaryngologic Clinics of North America. 2005; 38:439-452 .

Citardi MJ, Batra PS, Kuhn FA. "Frontal Sinus Rescue." In: Kountakis S, Senior B, Draf W, ed., Frontal Sinus Disease. New York: Springer. 2005 (pp. 243-249)

2004 Peer-Reviewed Publications

Batra PS, Citardi MJ, Gallivan RP, Roh HJ, Lanza DC. "Software-enabled CT analysis of carotid artery position and sphenoid sinus pneumatization patterns." American Journal of Rhinology. 2004; 18:203-208.

Batra PS, Citardi MJ, Gallivan RP, Roh HJ, Lanza DC. "Software-enabled CT analysis of optic nerve position and paranasal sinus pneumatization patterns." Otolaryngology-Head & Neck Surgery. 2004; 131:940-945.

Batra PS, Roh H-J, Bolger WE, Lee J, Citardi MJ, Lanza DC. "Endoscopic resection of sinonasal malignancies: a preliminary report." Skull Base Surgery. 2004; 14:11.

Citardi MJ, Batra PS, Gallivan RP, Maurer CR, Rohfling R, Roh HJ, Lanza DC. "Quantitative computer-aided CT analysis of sphenoid sinus anatomical relationships." American Journal of Rhinology. 2004; 18:173-178.

Herrmann B, Citardi MJ, Vogler G, Gardner L, Smith G, Javer A, Burt HM, Jackson J, Kuhn FA. "A preliminary report on the effects of paclitaxel-impregnated stents on sheep nasal mucosa." American Journal of Rhinology. 2004; 18:119-124.

Knott, PD, Mauer CR, Gallivan RP, Roh, HJ, Citardi MJ. "The impact of fiducial distribution on headset based registration in image-guided sinus surgery." Otolaryngology-Head and Neck Surgery. 2004; 131:666-672.

Lee WT, Kuhn FA, Citardi MJ. "3D CT analysis of frontal recess anatomy in patients without frontal sinusitis." Otolaryngology-Head and Neck Surgery. 2004; 131:164-173.

Roh HJ, Batra PS, Citardi MJ, Lee J, Bolger WE, Lanza DC. "Endoscopic resection of malignancies: a preliminary report." American Journal of Rhinology. 2004; 18:239-252.

Roh HJ, Procop G, Batra PS, Citardi MJ, Lanza DC. "Inflammation and the pathogenesis of inverted papilloma." American Journal of Rhinology. 2004; 18:65-74.

Batra PS. "Radiologic imaging in rhinosinusitis." Cleve Clin J Med 71:886-8, 2004.

2004 Publications (Other)

Citardi MJ. "Cerebrospinal fluid rhinorrhea." In: Cummings, C, et al., ed. Otolaryngology-Head and Neck Surgery (4th edition). Philadelphia: Elsevier Science. 2004.

Fakhri S, Citardi, MJ. "Considerations against concurrent functional endoscopic sinus surgery and rhinoplasty." Facial Plastic Clinics of North America. 2004; 12:431-434.

Otology

The Otology Section also is recognized for excellence in clinical and basic science research in adult sensorineural hearing loss (SHL). Dr. Hughes is Cleveland Clinic's principal investigator in a NIH-funded, five-year, multicenter study of intratympanic steroid treatment for sudden SHL. In autoimmune SHL, Dr. Hughes is co-investigator in an NIH grant submitted March 1st by Vincent Tuohy PhD of the Lerner Research Institute.

Research Fellow Hyun-Min Park MD from Seoul, Korea assists Dr. Tuohy in the laboratory this year. Dr. Tuohy’s and Dr. Hughes’ combined work exemplifies the type of translational research encouraged by Cleveland Clinic.

Pediatric ENT

Dr. Hirose completed a grant awarded by the American Hearing Research Foundation and the results of this work culminated in a manuscript submitted to the Journal of Comparative Neurology in December of 2004. She received a third grant this year totaling $225,000 from the Royal National Institute for the Deaf. This most recent grant brings Dr. Hirose’s grant awards to a total of $1,305,000 of direct costs. Two abstracts from Dr. Hirose’s work were presented at the 2004 Midwinter Meeting of the Association for Research in Otolaryngology, both of which received significant attention.

Dr. Hirose has also mentored Dr. James Chan during the academic year 2003-2004 and Dr. Nathan Sautter during the academic year 2004-2005. Under the guidance of Dr. Hirose, both Drs. Chan and Sautter were awarded the Resident Research Grant for $10,000 through the American Academy of Otolaryngology-Head and Neck Surgery.

Dr. Krakovitz has taken the helm from Dr. Koltai for the subcontract on the grant awarded to the BIOMEC Corporation on ultrasonic detection of middle ear effusion. This project has received continued support through the NIH through a small business innovation research grant totaling $1,420,922 of direct costs.

Vestibular & Balance Disorders

Selected Publications:

Hreib K, White J, Lucey M. "Cranial Nerve VIII — Vestibular." Netter’s Neurology, Ed. H. Royden Jones, Jr., MD, ICON Publishing, Teterboro New Jersey, 2005

White J, Oas J. "Apogeotropic nystagmus in lateral semicircular canal benign paroxysmal positional vertigo." Neurology (suppl.1) 64(6):A12,2005.

White J. "Meniere’s and otosclerosis." Otoneurologia 2000 18:36-7, 2004.

White J. "Horizontal semicircular canal benign positional vertigo." Proceedings of the Barany Society XXIII International Congress, J. Vest. Res. 14(2,3):183-4, 2004.

White J. "Benign paroxysmal positional vertigo." Cleveland Clinic Journal of Medicine, September 2004.

White J, Coale K, Catalano P, Oas J. "Lateral semicircular canal benign positional vertigo, diagnosis and management." Otolaryngology-Head and Neck Surgery, in press

White J, Savvides P, Cherian N, Oas J. "Canalith repositioning for benign paroxysmal positional vertigo, an evidence based review." Otology and Neurotology, in press.

White J, Oas J. "Diagnosis and management of lateral semicircular canal conversions during particle repositioning therapy." Laryngoscope, in press.

White J, Oas J. "Meniere’s and migraine." Proceedings of the Fifth International Symposium on Meniere’s, Los Angeles, CA, 2005, in press.

White J. "Benign paroxysmal positional vertigo," in Practical Management Approaches to the Dizzy Patient, Ed. P. Weber, Thieme Publishing, NY, NY. In press.

White J, Coale K, Beaudoin K, Catalano P, Cohen N, Oas J.  "Postural control in elderly patients with benign paroxysmal positional vertigo." Submitted to Journal of Vestibular Research.

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