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Description
Inclusion Criteria
Exclusion Criteria
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Title Circulating BRAF in the Diagnosis of Differentiated Thyroid Cancer among patients with thyroid nodules: Pilot Study for Clinical Validation of a highly sensitive allele specific quantitative RT-PCR and melt curve analysis based assay for BRAF.
IRB CASE 2314
CC 13-1462
Hospital Main Campus
Disease Thyroid
Description
- Analytical validation of a quantitative PCR and melting curve analysis based assay for determination of BRAF mutation in DNA isolated from circulating thyroid cells [CTCs] and FNA specimen.
- 2. To evaluate its clinical efficacy in the preoperative diagnosis of differentiated thyroid cancer in blood and in indeterminate FNA specimens.
Inclusion Criteria
- Patients presenting with the suspected or confirmed diagnosis of thyroid carcinoma and require surgery.
- Able to understand the consent form.
Exclusion Criteria
- Unable to understand the consent form.