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TOG 1311   |   CC00195
A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511

Main Campus
Phase 2
Flucytosine (5-FC)

Contact Information
Cancer Answer Line


8:00 am - 4:30 pm, Monday - Friday

Primary Objective
  • To allow for extended safety observations as required by the guidelines for patients enrolled in gene transfer studies.
Secondary Objectives
  • Efficacy for subjects will be reported in the parent study.
Exploratory Objective
  • To assess safety and preliminary efficacy of Toca 511 when reinjected in selected subjects followed by treatment with Toca FC.

Inclusion Criteria
  1. Has the subject given written informed consent?
  2. Has the subject received Toca 511 in a prior study?
  3. Is the subject willing and able to abide by the protocol?

Exclusion Criteria
  1. If the subject elects to continue with Toca FC, does the subject have a history of allergy or intolerance to flucytosine?

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