Study:
Severe Asthma Research Program
Rationale:
n/a
Purpose:
The investigators will study the biologic and chemical differences that cause the greater
incidence, and severity of asthma in women as compared to men. Severe asthma affects boys
more than girls, while severe asthma in adults is predominantly a disease of women. The
investigators aim to identify the processes that occur in the body that are behind the onset
of severe asthma in young women during the teenage years, and the resolution of severe
asthma in boys. To further evaluate gender influences on asthma, asthmatic women at
different stages of their menstrual cycle (period) will be also studied. The investigators
aim to use biomarkers to develop testing procedures that will identify different types or
characteristics of asthma in men and women; and to follow patients over time to uncover
relevant clinical outcomes of biomarkers. The investigators anticipate that they will 1)
develop clinically relevant tests to identify unique types or characteristics of asthma and
severe asthma; 2) determine outcomes over time of biochemically-defined types of asthma; and
3) identify the reasons for why adult women are affected more than men with severe asthma.
Study Status: Recruiting
Recruiting:
Emmea Mattox 216-445-1756
| Condition |
Intervention |
Phase |
|
Asthma |
n/a |
N/A |
Verified by
The Cleveland Clinic
January, 2013
Sponsored by: The Cleveland Clinic
Information provided by: The Cleveland Clinic
ClinicalTrials.gov identifier: NCT01759186
Study Type: Interventional
Study Design: Observational Model: Cohort, Time Perspective: Prospective
Cleveland Clinic
Cleveland, Ohio 44195
United States
Serpil C Erzurum, MD., Principal Investigator
Benjamin Gaston, MD., Principal Investigator
W. Gerald Teague, MD., Principal Investigator