Study:
Ureteroscopic Treatment of Intrarenal Stones - A Comparative Analysis of "Dusting" Versus "Basketing" With Holmium Laser Lithotripsy
Rationale:
n/a
Purpose:
The purpose of this study is to evaluate outcomes of an established procedure for treatment
of kidney stones that are present within the inner aspect of the kidney. This procedure is
called flexible ureteroscopy, which involves placing a small camera through the urethra
while anesthetized (asleep), up the ureter (the tube connecting kidney and bladder) and into
the kidney to the kidney stone. Then, the stone is broken into tiny fragments using a small
laser called a Holmium laser. While this treatment is a well-established option for
treatment of these stones, there are several different techniques used to help eliminate
them from the kidney. Some urologists treat the stone by a method called "active"
extraction whereby the ureteroscope is passed back and forth into the kidney to remove all
visible stone fragments. Others use a method called "dusting" whereby the stones are broken
into tiny fragments or "dust" with the intention that achieving such a small stone size will
allow the stones to pass spontaneously. There has not been a systematic and rigorous
comparison of these techniques in terms of treatment outcomes. By collecting information on
the success of treatment, the investigators hope to provide benchmark data for future
studies of kidney stone treatment and improve the care of all patients who need surgery for
their kidney stones.
The investigators hypothesize that the stone free rate for renal stone(s) 5-15 mm is around
90% and that the stone clearance rate with be 20% higher in those patients that undergo
complete stone fragment extraction versus those that undergo stone dusting (residual
fragments < 2mm).
Study Status: Recruiting
Recruiting:
Carl Sarkissian sarkisc@ccf.org
| Condition |
Intervention |
Phase |
Kidney Calculi
Kidney Stones
Nephrolithiasis
Renal Stones |
n/a |
N/A |
Verified by
Mayo Clinic
April, 2013
Sponsored by: Mayo Clinic
Information provided by: Mayo Clinic
ClinicalTrials.gov identifier: NCT01619735
Study Type: Interventional
Study Design: Observational Model: Cohort, Time Perspective: Prospective
Cleveland Clinic
Cleveland, Ohio 44195
United States
Mitchell Humphreys, MD., Principal Investigator