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Associating Renal Transplantation With the ITN Signature of Tolerance


An Observational Study to Assess the Prevalence of a Tolerance Signature in Renal Transplant Recipients (ITN524ST/CTOT-12)




This is an observational study for people who have received a kidney transplant within the past 1 to 5 years. Researchers in this study are looking for a certain pattern of genes and cells in the blood that has been found in a group of rare transplant patients who do not need immunosuppression. The study goal is to find out how common this pattern is in transplant patients, as a first step in determining if it can be used to personalize anti-rejection drug regimens better.

Study Status: Active, not recruiting


Condition Intervention Phase
Kidney Transplantation n/a N/A

Verified by National Institute of Allergy and Infectious Disease (NIAID) January, 2012

Sponsored by: National Institute of Allergy and Infectious Disease (NIAID)
Information provided by: National Institute of Allergy and Infectious Disease (NIAID) identifier: NCT01516177

Study Type: Interventional

Study Design: Observational Model: Cohort, Time Perspective: Prospective

The Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

Anil Chandraker, MD., Study Chair
Kenneth Newell, MD, PhD., Study Chair
Laurence Turka, MD., Study Chair

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