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Correlating Outcomes With Biochemical Markers to Estimate Time-progression in Idiopathic Pulmonary Fibrosis (IPF)


COMET: Correlating Outcomes With Biochemical Markers to Estimate Time-progression in IPF. A Prospective, Multi-Center, Longitudinal Follow up Study of Subjects With Idiopathic Pulmonary Fibrosis




Study purpose: The disease course of idiopathic pulmonary fibrosis (IPF) is variable. During the course of the disease some patients will get better, some will stay the same, and others will get worse. Currently doctors do not have any way to predict an individual patients disease course. The purpose of this study is to determine if `biomarkers` such as proteins or genes isolated at the time of diagnosis can be used to predict the disease course. These `biomarkers` will be obtained from samples of blood, from a procedure call a bronchoscopy, and in some patients from extra tissue obtained by a surgical lung biopsy.

Study Status: Completed


Condition Intervention Phase
Idiopathic Pulmonary Fibrosis n/a N/A

Verified by University of Michigan November, 2009

Sponsored by: University of Michigan
Information provided by: University of Michigan identifier: NCT01071707

Study Type: Interventional

Study Design: Observational Model: Case-Only, Time Perspective: Prospective

Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

Herbert Reynolds, MD., Study Director
Fernando J Martinez, MD,MS., Principal Investigator
Galen B Toews, MD., Principal Investigator
Kevin R Flaherty, MD, MS., Principal Investigator

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