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Dopamine in Acute Decompensated Heart Failure II


Comparison of High-dose Furosemide, Low-dose Furosemide, and the Combination of Low-dose Furosemide and Low-dose Dopamine in Patients With Acute Decompensated Heart Failure




The aim of this study is to compare the effects of 1) high-dose furosemide, 2) low-dose furosemide, and 3) low-dose furosemide combined with low-dose dopamine on diuresis, clinical status, renal function, electrolyte balance, length of stay, and 60-day post-discharge outcomes in patients hospitalized with acute decompensated heart failure.

Study Status: Terminated


Condition Intervention Phase
Acute Decompensated Heart Failure Drug: High-dose furosemide
Drug: Low-dose furosemide
Drug: Low-dose furosemide combined with low-dose dopamine
Phase 4

Verified by Larissa University Hospital September, 2013

Sponsored by: Larissa University Hospital
Information provided by: Larissa University Hospital identifier: NCT01060293

Study Type: Interventional

Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

The Cleveland Clinic Foundation
Cleveland, Ohio
United States

Gregory Giamouzis, MD., Study Chair
Filippos Triposkiadis, MD., Study Chair

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