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Brivanib Alaninate in Treating Patients With Recurrent or Persistent Endometrial Cancer


A Phase II Evaluation of Brivanib (BMS582664), an Oral, Multitargeted Growth Factor Tyrosine Kinase Inhibitor in the Treatment of Recurrent or Persistent Endometrial Carcinoma


Brivanib alaninate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.


This phase II trial is studying how well brivanib alaninate works in treating patients with recurrent or persistent endometrial cancer.

Study Status: Active, not recruiting


Condition Intervention Phase
Endometrial Cancer Drug: brivanib alaninate Phase 2

Verified by Gynecologic Oncology Group December, 2010

Sponsored by: Gynecologic Oncology Group
Information provided by: National Cancer Institute (NCI) identifier: NCT00888173

Study Type: Interventional

Study Design: Masking: Open Label, Primary Purpose: Treatment

Cleveland Clinic Cancer Center at Fairview Hospital
Cleveland, Ohio 44111
United States

Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States

Matthew A. Powell, MD., Study Chair

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