Study:
Prospective, Randomized, Multi-Center Trial of Initial Trophic Enteral Feeding Followed by Advancement to Full-Calorie Enteral Feeding vs. Early Advancement to Full-Calorie Enteral Feeding in Patients With Acute Lung Injury (ALI) or Acute Respiratory Distress Syndrome (ARDS)
Rationale:
n/a
Purpose:
Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are medical
conditions that occur when there is severe inflammation and increased fluids in both lungs,
making it difficult for the lungs to function properly. Hospital treatment for a person with
ALI/ARDS often includes the use of a breathing machine, or ventilator, until the person is
able to breathe without assistance. Initiating proper nutrition through a feeding tube early
in a person`s hospital stay may help to improve recovery, but the optimal timing,
composition, and amount of feeding treatments remain unknown. This study will evaluate
whether early or delayed full-calorie feeding through a feeding tube is more effective in
reducing recovery time and increasing survival rates in people with ALI/ARDS.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
|
Respiratory Distress Syndrome, Adult |
Behavioral: Minimal (Trophic) Feeding
Behavioral: Full Feeding |
Phase 3 |
Verified by
National Heart, Lung, and Blood Institute (NHLBI)
February, 2012
Sponsored by: National Heart, Lung, and Blood Institute (NHLBI)
Information provided by: National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov identifier: NCT00883948
Study Type: Interventional
Study Design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Cleveland Clinic Foundation
Cleveland, Ohio
United States
Arthur P. Wheeler, MD., Study Chair