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AST-120 Used to Treat Mild Hepatic Encephalopathy


A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Trial to Evaluate the Efficacy, Safety and Tolerability of AST-120 (Spherical Carbon Adsorbent) for 8 Weeks in the Treatment of Mild Hepatic Encephalopathy




The purpose of this study is to determine whether AST-120 is safe and effective in the treatment of mild hepatic encephalopathy.

Study Status: Completed


Condition Intervention Phase
Mild Hepatic Encephalopathy Drug: AST-120 Phase 2

Verified by Ocera Therapeutics June, 2010

Sponsored by: Ocera Therapeutics
Information provided by: Ocera Therapeutics identifier: NCT00867698

Study Type: Interventional

Study Design: Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

Jeff Bornstein, MD., Study Director

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