Study:
Improved Understanding of the Biology and Use of TNF Inhibition in Children With JIA
Rationale:
n/a
Purpose:
Polyarticular juvenile idiopathic arthritis (Poly JIA) is a form of juvenile arthritis,
which is a chronic disease affecting approximately 250,000 people younger than 16 years of
age. Poly JIA can be treated with anti-tumor necrosis factor (anti-TNF), a type of
medication that is often effective but also has some toxic side effects and is expensive.
Among those with poly JIA who are effectively treated with anti-TNF, some can remain healthy
off the medication, but some begin to feel the effects of their disease again once the
medication is stopped. This study will attempt to find whether certain tests or signs can
predict which people with poly JIA can safely stop their anti-TNF medications.
Study Status: Active, not recruiting
Recruiting:
n/a
| Condition |
Intervention |
Phase |
|
Juvenile Idiopathic Arthritis |
Other: Withdrawal of anti-TNF therapy |
Phase 4 |
Verified by
Children`s Hospital Medical Center, Cincinnati
May, 2013
Sponsored by: Children`s Hospital Medical Center, Cincinnati
Information provided by: Children`s Hospital Medical Center, Cincinnati
ClinicalTrials.gov identifier: NCT00792233
Study Type: Interventional
Study Design: Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States
Daniel J. Lovell, MD., Principal Investigator