Study:
Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis--The ATTRACT Trial
Rationale:
n/a
Purpose:
The purpose of this study is to determine if the use of adjunctive Pharmacomechanical
Catheter Directed Thrombolysis, which includes the intrathrombus administration of
rt-PA--Activase (Alteplase),can prevent the post-thrombotic syndrome(PTS)in patients with
symptomatic proximal deep vein thrombosis(DVT)as compared with optimal standard DVT therapy
alone.
Study Status: Recruiting
Recruiting:
Jackie McCluskey, RN 216-444-4803 mcclusj@ccf.org
| Condition |
Intervention |
Phase |
Deep Vein Thrombosis
Venous Thrombosis
Postphlebitic Syndrome
Venous Thromboembolism
Post Thrombotic Syndrome |
Drug: Recombinant tissue plasminogen activator (rt-PA) |
Phase 3 |
Verified by
Washington University School of Medicine
May, 2013
Sponsored by: Washington University School of Medicine
Information provided by: Washington University School of Medicine
ClinicalTrials.gov identifier: NCT00790335
Study Type: Interventional
Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Cleveland Clinic
Cleveland, Ohio 44195
United States
Suresh Vedantham, M.D.., Principal Investigator
Clive Kearon, MB, MRCP, FRCP(C), PhD., Principal Investigator
Samuel Z Goldhaber, M.D.., Study Chair