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Cryotherapy for Barrett`s Esophagus and Early Esophageal Cancers


A Pilot Study of Cryotherapy for Barrett`s Esophagus With High-Grade Dysplasia and Early Esophageal Cancers




This is a single center study to evaluate the efficacy and safety of a new ablation technique involving the spray of liquid nitrogen through a catheter (cryotherapy) via an upper endoscopy (EGD) to ablate Barrett`s esophagus with changes of high-grade dysplasia (HGD) or intramucosal cancer (IMCA) and patients with esophageal cancer limited to the esophageal wall, in whom there are no standard treatment options available.

Study Status: Completed


Condition Intervention Phase
Barretts Esophagus
Esophageal Cancer
Procedure: Cryospray Ablation Phase 0

Verified by Case Comprehensive Cancer Center December, 2012

Sponsored by: Case Comprehensive Cancer Center
Information provided by: Case Comprehensive Cancer Center identifier: NCT00650988

Study Type: Interventional

Study Design: Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

The Cleveland Clinic
Cleveland, Ohio 44195
United States

John A. Dumot, D.O.., Principal Investigator

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