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Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip Replacement

Study:

Effect of Intrathecal Ketorolac on Mechanical Hypersensitivity After Total Hip Arthroplasty

Rationale:

n/a

Purpose:

Chronic pain in patients following total hip replacement seems to be a significant problem. Previous research has shown that more effective pain management in the early postoperative period may decrease the incidence of the development of chronic pain states. This study will evaluate whether ketorolac (a non steroidal anti-inflammatory drug) given into the spinal fluid before surgery will reduce the area of sensitivity (or pain to light touch) following surgery. Patients will be monitored during their postoperative hospital stay and then contacted by telephone at 8 weeks and 6 months after surgery and questioned about any pain they are having at their surgical site. Patients that are still experiencing pain at 6 months will be asked to return to the medical center for the study staff to assess their pain or sensitivity at the surgical site.

Study Status: Active, not recruiting

Recruiting:
n/a

Condition Intervention Phase
Hip Arthroplasty Drug: ketorolac tromethamine opthalmic solution
Drug: placebo
Phase 2

Verified by James C. Eisenach, M.D. February, 2012

Sponsored by: James C. Eisenach, M.D.
Information provided by: Wake Forest University
ClinicalTrials.gov identifier: NCT00621530

Study Type: Interventional

Study Design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

The Cleveland Clinic Foundation
Cleveland, Ohio 44120
United States

James C. Eisenach, MD., Principal Investigator

This information is abridged to display results relevant only to Cleveland Clinic. To see complete record visit ClinicalTrials.gov
  Information obtained from ClinicalTrials.gov on
Link to the current ClinicalTrials.gov record.

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