Study:
Effect of Intrathecal Ketorolac on Mechanical Hypersensitivity After Total Hip Arthroplasty
Rationale:
n/a
Purpose:
Chronic pain in patients following total hip replacement seems to be a significant problem.
Previous research has shown that more effective pain management in the early postoperative
period may decrease the incidence of the development of chronic pain states.
This study will evaluate whether ketorolac (a non steroidal anti-inflammatory drug) given
into the spinal fluid before surgery will reduce the area of sensitivity (or pain to light
touch) following surgery. Patients will be monitored during their postoperative hospital
stay and then contacted by telephone at 8 weeks and 6 months after surgery and questioned
about any pain they are having at their surgical site. Patients that are still experiencing
pain at 6 months will be asked to return to the medical center for the study staff to assess
their pain or sensitivity at the surgical site.
Study Status: Active, not recruiting
Recruiting:
n/a
| Condition |
Intervention |
Phase |
|
Hip Arthroplasty |
Drug: ketorolac tromethamine opthalmic solution
Drug: placebo |
Phase 2 |
Verified by
James C. Eisenach, M.D.
February, 2012
Sponsored by: James C. Eisenach, M.D.
Information provided by: Wake Forest University
ClinicalTrials.gov identifier: NCT00621530
Study Type: Interventional
Study Design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
The Cleveland Clinic Foundation
Cleveland, Ohio 44120
United States
James C. Eisenach, MD., Principal Investigator