Study:
Diagnostic Two and Three Dimensional Echocardiography Study Protocol
Rationale:
n/a
Purpose:
The purpose of this study is to perform ground-based research to study what happens to the
heart muscle in space. People who have problems with their aortic valve have an increase in
the amount of muscle in the left ventricle of the heart. After valve surgery, the amount of
muscle should decrease and return to normal. Astronauts lose heart muscle mass during space
flight. Our study will look at these changes in your heart, which we believe are similar to
what happens during long term space travel.
This study will look at the accuracy of three dimensional ultrasound imaging (echo) in
monitoring the changes in heart size and function following aortic valve replacement. We are
studying ways to prevent health-related problems that men and women will face on
long-duration space missions.
The hypothesis is that serial two dimensional and three dimensional echo will show accurate
changes in the left ventricle mass and volume following aortic valve replacement for aortic
stenosis or regurgitation
Study Status: Enrolling by invitation
Recruiting:
n/a
| Condition |
Intervention |
Phase |
Aortic Valve Stenosis
Aortic Valve Insufficiency |
n/a |
N/A |
Verified by
The Cleveland Clinic
January, 2008
Sponsored by: The Cleveland Clinic
Information provided by: The Cleveland Clinic
ClinicalTrials.gov identifier: NCT00598754
Study Type: Interventional
Study Design: Cohort, Prospective
Cleveland Clinic
Cleveland, Ohio 44195
United States
Jim D Thomas, MD., Principal Investigator