Study:
Echocardiographic Assessment of Cardiovascular Adaptation and Counter Measures n Microgravity
Rationale:
n/a
Purpose:
The National Space Biomedical Research Institute is interested in learning more about heart
function in space. One potential problem with long duration, manned space flight is muscle
loss- including loss of heart muscle. One goal of our research is to help identify why this
muscle loss occurs. We are interested in patients undergoing aortic valve surgery because
this procedure is performed to correct a problem with the valve that may also change heart
function. This change in heart function may provide information that is useful in
understanding and potentially preventing the loss of cardiac muscle in space.
Three patient groups will be studied, patients having surgery for aortic regurgitation,
aortic stenosis, and coronary bypass. We are planing to perform this study on 30 patients,
10 in each group.
The aim of this study is to continue our ongoing study of the magnitude and predictors of the
changes in size of the left ventricle following acute volume and pressure unloading as a
ground-based analog for manned space flight.
Study Status: Recruiting
Recruiting:
Roberta Palumbo, RN 216-444-8778 palumbr@ccf.org
| Condition |
Intervention |
Phase |
Aortic Valve Insufficiency
Aortic Valve Stenosis |
n/a |
N/A |
Verified by
The Cleveland Clinic
January, 2008
Sponsored by: The Cleveland Clinic
Information provided by: The Cleveland Clinic
ClinicalTrials.gov identifier: NCT00598598
Study Type: Interventional
Study Design: Cohort, Prospective
Cleveland Clinic
Cleveland, Ohio 44195
United States
Jim Thomas, MD., Principal Investigator