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Intraperitoneal Paclitaxel, Doxorubicin, and Cisplatin in Treating Patients With Endometrial Cancer


A Phase I Study of IV Doxorubicin Plus Intraperitoneal (IP) Paclitaxel and IV or IP Cisplatin in Endometrial Cancer Patients at High Risk for Peritoneal Failure


Drugs used in chemotherapy, such as paclitaxel, doxorubicin, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving them in different ways may kill more tumor cells.


This phase I trial is studying the side effects and best dose of intraperitoneal paclitaxel when given together with doxorubicin and cisplatin in treating patients with endometrial cancer.

Study Status: Recruiting

Clinical Trials Office - Cleveland Clinic Taussig Cancer Cente 866-223-8100

Condition Intervention Phase
Endometrial Cancer
Ovarian Cancer
Drug: cisplatin
Drug: doxorubicin hydrochloride
Drug: filgrastim
Drug: paclitaxel
Drug: pegfilgrastim
Phase 1

Verified by Gynecologic Oncology Group August, 2008

Sponsored by: Gynecologic Oncology Group
Information provided by: National Cancer Institute (NCI) identifier: NCT00575952

Study Type: Interventional

Study Design: Treatment

Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States

D. Scott McMeekin, MD., Study Chair

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