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Intraperitoneal Paclitaxel, Doxorubicin, and Cisplatin in Treating Patients With Endometrial Cancer

Study:

A Phase I Study of IV Doxorubicin Plus Intraperitoneal (IP) Paclitaxel and IV or IP Cisplatin in Endometrial Cancer Patients at High Risk for Peritoneal Failure

Rationale:

Drugs used in chemotherapy, such as paclitaxel, doxorubicin, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving them in different ways may kill more tumor cells.

Purpose:

This phase I trial is studying the side effects and best dose of intraperitoneal paclitaxel when given together with doxorubicin and cisplatin in treating patients with endometrial cancer.

Study Status: Recruiting

Recruiting:
Clinical Trials Office - Cleveland Clinic Taussig Cancer Cente 866-223-8100

Condition Intervention Phase
Endometrial Cancer
Ovarian Cancer		 Drug: cisplatin
Drug: doxorubicin hydrochloride
Drug: filgrastim
Drug: paclitaxel
Drug: pegfilgrastim		 Phase 1

Verified by Gynecologic Oncology Group August, 2008

Sponsored by: Gynecologic Oncology Group
Information provided by: National Cancer Institute (NCI)
ClinicalTrials.gov identifier: NCT00575952

Study Type: Interventional

Study Design: Treatment

Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States

D. Scott McMeekin, MD., Study Chair

This information is abridged to display results relevant only to Cleveland Clinic. To see complete record visit ClinicalTrials.gov
  Information obtained from ClinicalTrials.gov on
Link to the current ClinicalTrials.gov record.