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Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival


Correlation of Donor Proinflammatory mRNA Profiles With Early Outcomes of Thoracic and Abdominal Transplantation




Activity of genes in donor tissues that are involved in inflammation are thought to be involved with early organ dysfunction, increased immune responses in transplant recipients, and organ rejection. The purpose of this study is to determine the relationship between genetic expression in donor and recipient tissue with transplant survival. Participants in this study will have received heart, lung, liver, or kidney transplants.

Study Status: Completed


Condition Intervention Phase
Heart Transplantation
Kidney Transplantation
Liver Transplantation
Lung Transplantation
n/a N/A

Verified by National Institute of Allergy and Infectious Diseases (NIAID) April, 2013

Sponsored by: National Institute of Allergy and Infectious Diseases (NIAID)
Information provided by: National Institute of Allergy and Infectious Diseases (NIAID) identifier: NCT00531921

Study Type: Interventional

Study Design: Observational Model: Case-Only, Time Perspective: Prospective

Cleveland Clinic Foundation (heart)
Cleveland, Ohio 44195
United States

Abraham Shaked, MD, PhD., Principal Investigator

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