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A Study Evaluating the Efficacy and Safety of Sunitinib With or Without Bevacizumab in First-Line Patients With Metastatic Renal Cell Cancer (SABRE-R)

Study:

A Multicenter, Phase II, Randomized, Blinded, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Sutent With or Without Bevacizumab in First-Line Patients With Metastatic Renal Cell Cancer

Rationale:

n/a

Purpose:

This is a Phase II, multicenter, randomized, blinded, placebo-controlled study designed to evaluate the safety and efficacy of combining bevacizumab with sunitinib relative to placebo with sunitinib in patients with metastatic RCC who have not received prior systemic therapy for metastatic disease. The study will enroll approximately 100 patients at approximately 20 centers in the United States.

Study Status: Terminated

Recruiting:
n/a

Condition Intervention Phase
Renal Cell Carcinoma Drug: bevacizumab
Drug: sunitinib
Drug: placebo		 Phase 2

Verified by Genentech February, 2008

Sponsored by: Genentech
Information provided by: Genentech
ClinicalTrials.gov identifier: NCT00491738

Study Type: Interventional

Study Design: Treatment, Randomized, Double Blind (Subject, Investigator), Placebo Control, Parallel Assignment

Cleveland Clinic Foundation
Cleveland, Ohio 44111
United States

Frank Scappaticci, M.D., Ph.D.., Study Director

This information is abridged to display results relevant only to Cleveland Clinic. To see complete record visit ClinicalTrials.gov
  Information obtained from ClinicalTrials.gov on
Link to the current ClinicalTrials.gov record.