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DEfibrillators To REduce Risk by MagnetIc ResoNance Imaging Evaluation


DEfibrillators To REduce Risk by MagnetIc ResoNance Imaging Evaluation




This trial is a prospective, multi-center, randomized study of patients with coronary artery disease (CAD) and mild to moderate left ventricular (LV) dysfunction. The primary objective of this study is to test the hypothesis that Implantable Cardioverter Defibrillator (ICD) therapy in combination with medical therapy in patients with an infarct size greater than or equal to 10% of the left ventricular mass improves long term survival compared to medical therapy alone. In addition to the 2-arm randomized trial, the study will also include a non-investigational registry of non-randomized patients.

Study Status: Terminated


Condition Intervention Phase
Coronary Artery Disease
Left Ventricular Dysfunction
Sudden Cardiac Death
Device: Defibrillator
Other: Control

Verified by St. Jude Medical March, 2012

Sponsored by: St. Jude Medical
Information provided by: St. Jude Medical identifier: NCT00487279

Study Type: Interventional

Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

The Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

Alan Kadish, MD., Principal Investigator

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