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A Phase I Trial of a Single Intravitreal Injection of REDD14NP to Patients With CNV Secondary to Wet AMD


A Phase 1 Open-Label, Dose Escalation Trial of REDD14NP Delivered by a Single Intravitreal Injection to Patients With Choroidal Neovascularization (CNV) Secondary to Exudative Age-Related Macular Degeneration ("Wet AMD")




This is an open-label, dose escalation study in which patents will receive a single intravitreal injection of REDD14NP. The primary objective of the study is to determine the safety and pharmacokinetics of REDD14NP when administered as a single intravitreal injection.

Study Status: Recruiting

Lynn Bartko, RN, BSN 216-444-7137

Condition Intervention Phase
Age-Related Macular Degeneration (AMD) Drug: REDD14NP Phase 1

Verified by Quark Pharmaceuticals October, 2007

Sponsored by: Quark Pharmaceuticals
Information provided by: Quark Pharmaceuticals identifier: NCT00455481

Study Type: Interventional

Study Design: Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety Study

Cole Eye Institute Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

James M Klancnik, MD., Principal Investigator

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