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Longitudinal Protocol for Granulomatosis With Polyangiitis (Wegener`s) and Microscopic Polyangiitis


Determining Disease Activity Biomarkers in Individuals With Granulomatosis With Polyangiitis (Wegener`s) and Microscopic Polyangiitis




Granulomatosis with polyangiitis (Wegener`s) (GPA) and microscopic polyangiitis (MPA) are two rare immune system disorders that cause the inflammation of blood vessels, or vasculitis. In order to properly treat these diseases, it is critical that the level of disease activity can be determined over the course of the disease. The purpose of this study is to determine new biological markers, or biomarkers, that may be used to assess the severity of disease in people with GPA or MPA.

Study Status: Recruiting

Katie Gartner 216-445-1397

Condition Intervention Phase
Granulomatosis With Polyangiitis
Microscopic Polyangiitis
n/a N/A

Verified by University of Pennsylvania November, 2013

Sponsored by: University of Pennsylvania
Information provided by: University of Pennsylvania identifier: NCT00315393

Study Type: Interventional

Study Design: Observational Model: Cohort, Time Perspective: Prospective

Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

Peter A. Merkel, MD, MPH., Study Chair

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