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BRAIN (Biomarker Rapid Assessment of Ischemic iNjury)


BRAIN (Biomarker Rapid Assessment of Ischemic iNjury)




This project is designed to evaluate the clinical utility of a novel blood test, the Triage Stroke Panel, as an aid in the diagnosis and assessment of stroke. The Triage Stroke Panel test device, used with the Triage MeterPlus, is a rapid, point-of-care immunoassay. The test measures the concentration of various analytes present in EDTA-anticoagulated whole blood or plasma, specifically B-type natriuretic peptide (BNP), fibrin degradation products containing D-Dimer, matrix metalloproteiase-9 (MMP-9), and S-100B. The test utilizes a proprietary algorithm for the automatic calculation of a single Multimarker Index (MMX) result from the individual biomarker values. The MMX result is being evaluated for use as an aid in the assessment and diagnosis of stroke.

Study Status: Completed


Condition Intervention Phase
Stroke Mimic(Conditions Presenting With Stroke-Like Conditions)
n/a Phase 2/Phase 3

Verified by Biosite April, 2006

Sponsored by: Biosite
Information provided by: Biosite identifier: NCT00206908

Study Type: Interventional

Study Design: Cross-Sectional, Convenience Sample, Retrospective Study

Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

Daniel Laskowitz, MD., Principal Investigator

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