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A Study to Evaluate the Efficacy of Bevacizumab in Combination With Tarceva for Advanced Non-Small Cell Lung Cancer


A Phase III, Multicenter, Placebo-Controlled, Double-Blind, Randomized Clinical Trial to Evaluate the Efficacy of Bevacizumab in Combination With Tarceva (Erlotinib) Compared With Tarceva Alone for Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) After Failure of Standard First-Line Chemotherapy




This is a Phase III, multicenter, placebo-controlled, double-blind, randomized study. Approximately 650 patients will be randomized in a 1:1 ratio to one of two treatment arms.

Study Status: Active, not recruiting


Condition Intervention Phase
Non-Small Cell Lung Cancer Drug: bevacizumab
Drug: erlotinib HCl
Drug: placebo
Phase 3

Verified by Genentech December, 2007

Sponsored by: Genentech
Information provided by: Genentech identifier: NCT00130728

Study Type: Interventional

Study Design: Treatment, Randomized, Double Blind (Subject, Investigator), Placebo Control, Parallel Assignment

Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

Paula O`Connor, M.D.., Study Director

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