Study:
A Phase II Evaluation of Cetuximab (C225, NSC #714692) in Combination With Carboplatin (NSC #241240) in the Treatment of Recurrent Platinum-Sensitive Ovarian or Primary Peritoneal Cancer
Rationale:
Monoclonal antibodies such as cetuximab can locate tumor cells and either kill
them or deliver tumor-killing substances to them without harming normal cells. Drugs used in
chemotherapy such as carboplatin work in different ways to stop tumor cells from dividing so
they stop growing or die. Combining cetuximab with carboplatin may kill more tumor cells.
Purpose:
This phase II trial is studying how well giving cetuximab together with carboplatin
works in treating patients with recurrent ovarian epithelial cancer or primary peritoneal
cancer.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
Ovarian Cancer Primary Peritoneal Cavity Cancer |
Biological: cetuximab Drug: carboplatin |
Phase 2 |
Verified by
Gynecologic Oncology Group
September, 2005
Sponsored by: Gynecologic Oncology Group
Information provided by: National Cancer Institute (NCI)
ClinicalTrials.gov identifier: NCT00086892
Study Type: Interventional
Study Design: Masking: Open Label, Primary Purpose: Treatment
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44124
United States
Angeles A. Secord, MD., Study Chair
Deborah K. Armstrong, MD.,
Nita Maihle, PhD.,