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Comparing Angiomax to Heparin With Protamine Reversal in Patients OPCAB


A Study Comparing Angiomax (Bivalirudin) to Heparin With Protamine Reversal in Patients Undergoing Coronary Artery Bypass (OPCAB) Surgery




The purpose of this study is to examine the safety and efficacy of Angiomax as an alternative anticoagulant to heparin with protamine reversal in patients undergoing off-pump coronary artery bypass graft surgery.

Study Status: Completed


Condition Intervention Phase
Cardiac Surgery
Coronary Artery Bypass Surgery
Drug: Bivalirudin
Drug: Heparin
Drug: Protamine
Phase 3

Verified by The Medicines Company November, 2011

Sponsored by: The Medicines Company
Information provided by: The Medicines Company identifier: NCT00073593

Study Type: Interventional

Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States

Andrew Sternlicht, MD., Study Director

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