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Combination Chemotherapy in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer


Randomized Phase III Trial Of Doxorubicin/Cisplatin/Paclitaxel And G-CSF Versus Carboplatin/Paclitaxel In Patients With Stage III & IV Or Recurrent Endometrial Cancer


Drugs used in chemotherapy such as doxorubicin, cisplatin, paclitaxel, and carboplatin use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective in treating endometrial cancer.


This randomized phase III trial is studying two combination chemotherapy regimens to compare how well they work in treating patients with stage III, stage IV, or recurrent endometrial cancer.

Study Status: Active, not recruiting


Condition Intervention Phase
Endometrial Cancer Biological: filgrastim
Drug: carboplatin
Drug: cisplatin
Drug: doxorubicin hydrochloride
Drug: paclitaxel
Phase 3

Verified by Gynecologic Oncology Group April, 2009

Sponsored by: Gynecologic Oncology Group
Information provided by: National Cancer Institute (NCI) identifier: NCT00063999

Study Type: Interventional

Study Design: Treatment, Randomized, Active Control

Cleveland Clinic Cancer Center at Fairview Hospital
Cleveland, Ohio 44111
United States

Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States

David S. Miller, MD., Study Chair

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