Study:
Phase I Study of Combined Radiotherapy and Arsenic Trioxide for the Treatment of Newly Diagnosed Malignant Glioma
Rationale:
Drugs such as arsenic trioxide may stop the growth of malignant glioma by
stopping blood flow to the tumor. Radiation therapy uses high-energy x-rays to damage tumor
cells. Combining arsenic trioxide with radiation therapy may kill more tumor cells.
Purpose:
This phase I trial is studying the side effects and best dose of arsenic trioxide
and radiation therapy in treating patients with newly diagnosed malignant glioma.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
|
Brain and Central Nervous System Tumors |
Drug: arsenic trioxide Radiation: radiation therapy |
Phase 1 |
Verified by
Sidney Kimmel Comprehensive Cancer Center
October, 2010
Sponsored by: Sidney Kimmel Comprehensive Cancer Center
Information provided by: Sidney Kimmel Comprehensive Cancer Center
ClinicalTrials.gov identifier: NCT00045565
Study Type: Interventional
Study Design: Primary Purpose: Treatment
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States
Samuel Ryu, MD., Study Chair