Study:
Effects of Talampanel on Patients With Advanced Parkinson`s Disease Who Have Been on Sinemet for More Than 5 Years and Have Dyskinesia (Abnormal Involuntary Movements)
Rationale:
n/a
Purpose:
The purpose of this research study is to test the safety and effectiveness of the study drug,
Talampanel, when used to treat patients with involuntary movements known as dyskinesias, as a
result of treatment to Parkinson`s disease.
It is not clear why people with Parkinson`s disease develop involuntary movements
(dyskinesias) but studies show that blocking receptors in the brain for a chemical called
glutamate decreases these movements. Talampanel is a drug which blocks these receptors.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
Dyskinesias Parkinson Disease Movement Disorders |
Drug: talampanel |
Phase 1/Phase 2 |
Verified by
IVAX Research LLC
March, 2008
Sponsored by: IVAX Research LLC
Information provided by: IVAX Research LLC
ClinicalTrials.gov identifier: NCT00036296
Study Type: Interventional
Study Design: Treatment
Cleveland Clinic Florida
Weston, Florida 33331
United States
n/a