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S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery


Smoking Cessation Intervention (Including Bupropion-Zyban Versus Placebo) for Completely Resected Stage I and II Non-Small Cell Lung Cancer Survivors Who Are Current Smokers


A program that includes bupropion may be more effective in helping early-stage lung cancer patients to quit smoking. It is not yet known if a program to quit smoking is more effective with or without bupropion.


Randomized phase III trial to determine the effectiveness of a program to quit smoking with or without bupropion in treating patients who have undergone surgery for stage I or stage II non-small cell lung cancer.

Study Status: Terminated


Condition Intervention Phase
Lung Cancer Behavioral: smoking cessation intervention
Drug: bupropion hydrochloride
Drug: nicotine
Procedure: psychosocial assessment and care
Phase 3

Verified by Southwest Oncology Group March, 2013

Sponsored by: Southwest Oncology Group
Information provided by: Southwest Oncology Group identifier: NCT00032084

Study Type: Interventional

Study Design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195-9001
United States

Ellen R. Gritz, PhD., Study Chair
Philip C. Hoffman, MD., Study Chair
James Stevenson, MD., Study Chair

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