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Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Primary or Recurrent Sarcoma

Study:

Phase II Study of Neoadjuvant Doxorubicin and Ifosfamide, Radiotherapy, and Surgical Resection in Patients With Primary or Recurrent Retroperitoneal Sarcoma

Rationale:

Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy, radiation therapy, and surgery may kill more tumor cells.

Purpose:

Phase II trial to study the effectiveness of combination chemotherapy, radiation therapy, and surgery in treating patients who have primary or recurrent sarcoma.

Study Status: Withdrawn

Recruiting:
n/a

Condition Intervention Phase
Stage III Adult Soft Tissue Sarcoma
Recurrent Adult Soft Tissue Sarcoma
Stage IVA Adult Soft Tissue Sarcoma
Stage IIB Adult Soft Tissue Sarcoma
Stage IIC Adult Soft Tissue Sarcoma
Drug: doxorubicin
Drug: filgrastim
Drug: ifosfamide
Procedure: biological response modifier therapy
Procedure: brachytherapy
Procedure: chemotherapy
Procedure: colony-stimulating factor therapy
Procedure: conventional surgery
Procedure: cytokine therapy
Procedure: intraoperative radiotherapy
Procedure: radiation therapy
Procedure: surgery
Phase 2

Verified by Radiation Therapy Oncology Group June, 2013

Sponsored by: Radiation Therapy Oncology Group
Information provided by: Radiation Therapy Oncology Group
ClinicalTrials.gov identifier: NCT00017160

Study Type: Interventional

Study Design: Primary Purpose: Treatment

Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States

Peter W. T. Pisters, MD., Study Chair

This information is abridged to display results relevant only to Cleveland Clinic. To see complete record visit ClinicalTrials.gov
  Information obtained from ClinicalTrials.gov on
Link to the current ClinicalTrials.gov record.

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