Study:
A Phase III Randomized Trial Of Paclitaxel And Carboplatin Versus Triplet Or Sequential Doublet Combinations In Patients With Epithelial Ovarian Or Primary Peritoneal Carcinoma
Rationale:
Drugs used in chemotherapy use different ways to stop tumor cells from dividing
so they stop growing or die. It is not yet known which combination chemotherapy regimen is
most effective in treating ovarian epithelial cancer and peritoneal cancer.
Purpose:
Randomized phase III trial to compare the effectiveness of various combination
chemotherapy regimens in treating patients who have stage III or stage IV ovarian cancer or
primary peritoneal cancer.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
Ovarian Cancer Primary Peritoneal Cavity Cancer |
Drug: carboplatin Drug: gemcitabine hydrochloride Drug: paclitaxel Drug: pegylated liposomal doxorubicin hydrochloride Drug: topotecan hydrochloride Procedure: adjuvant therapy Procedure: conventional surgery |
Phase 3 |
Verified by
Gynecologic Oncology Group
September, 2004
Sponsored by: Gynecologic Oncology Group
Information provided by: National Cancer Institute (NCI)
ClinicalTrials.gov identifier: NCT00011986
Study Type: Interventional
Study Design: Allocation: Randomized, Primary Purpose: Treatment
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195-9001
United States
Michael A. Bookman, MD., Study Chair
William P. McGuire, MD.,
Amy D. Tiersten, MD., Study Chair
Helen Pearce, PhD., Study Chair