Study:
Decompression Intervention of Variceal Rebleeding Trial
Rationale:
n/a
Purpose:
The Decompression Intervention of Variceal Rebleeding Trial (DIVERT) is a multi-center
prospective randomized clinical trial comparing the radiologic procedure of transjugular
intrahepatic portal-systemic shunt (TIPS) with the surgical procedure of distal splenorenal
shunt (DSRS) for variceal bleeding in patients with Child`s Class A and B cirrhosis.
This is recognized nationally and internationally as the study that will answer the question
as to which of these is the best treatment for decompression of varices in patients who have
failed endoscopic and pharmacologic therapy.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
Esophageal and Gastric Varices
Liver Cirrhosis |
Procedure: Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Procedure: Distal Splenorenal Shunt |
Phase 3 |
Verified by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
January, 2010
Sponsored by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
ClinicalTrials.gov identifier: NCT00006161
Study Type: Interventional
Study Design: Treatment, Randomized, Parallel Assignment, Safety/Efficacy Study
Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States
J. Michael Henderson, M.D.., Principal Investigator
Thomas D. Boyer, M.D.., Principal Investigator
Lennox Jeffers, M.D.., Principal Investigator
Enrique Molina, M.D.., Principal Investigator
Layton F. Rikkers, M.D.., Principal Investigator
Kareem Abu-Elmagd, M.D.., Principal Investigator
Amrik Shah, Sc.D.., Principal Investigator