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Combination Chemotherapy, Radiation Therapy, and RSR13 in Treating Patients With Stage III Non-small Cell Lung Cancer


A Phase II Study of Induction Chemotherapy With Paclitaxel and Carboplatin Followed by Radiation Therapy With RSR13 for Locally Advanced Inoperable Non-Small Cell Lung Cancer


Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as RSR13 may make tumor cells more sensitive to radiation therapy.


Phase II trial to study the effectiveness of combination chemotherapy, radiation therapy, and RSR13 in treating patients who have stage III non-small cell lung cancer that cannot be removed by surgery.

Study Status: Completed


Condition Intervention Phase
Lung Cancer Drug: carboplatin
Drug: chemotherapy
Drug: efaproxiral
Drug: paclitaxel
Radiation: radiation therapy
Phase 2

Verified by Spectrum Pharmaceuticals, Inc May, 2013

Sponsored by: Spectrum Pharmaceuticals, Inc
Information provided by: Spectrum Pharmaceuticals, Inc identifier: NCT00004202

Study Type: Interventional

Study Design: Primary Purpose: Treatment

Cleveland Clinic Cancer Center
Cleveland, Ohio 44195
United States

Hak Choy, MD., Study Chair

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