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Combination Chemotherapy in Treating Children With Neuroblastoma


Treatment for Infants and Children With Intermediate Risk Neuroblastoma: A Phase III Intergroup CCG/POG Study


Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. Combination chemotherapy plus surgery may be an effective treatment for neuroblastoma.


This phase III trial is studying how well combination chemotherapy followed by surgery works in treating young patients with neuroblastoma.

Study Status: Completed


Condition Intervention Phase
Neuroblastoma Biological: filgrastim
Biological: sargramostim
Drug: carboplatin
Drug: cyclophosphamide
Drug: doxorubicin hydrochloride
Drug: etoposide
Procedure: conventional surgery
Procedure: neoadjuvant therapy
Phase 3

Verified by Children`s Oncology Group November, 2010

Sponsored by: Children`s Oncology Group
Information provided by: National Cancer Institute (NCI) identifier: NCT00003093

Study Type: Interventional

Study Design: Masking: Open Label, Primary Purpose: Treatment

Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States

David L. Baker, MD, MBBS, FRACP, FRCPA., Study Chair

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