Study:
A Phase II Trial of Infusional 5-Fluorouracil (5-FU), Calcium Leucovorin (LV), Mitomycin-C (Mito-C), and Dipyridamole (D) in Patients With Locally Advanced Unresected Pancreatic Adenocarcinoma
Rationale:
Drugs used in chemotherapy use different ways to stop tumor cells from dividing
so they stop growing or die. Combining more than one drug may kill more tumor cells.
Chemotherapy following surgery may be an effective treatment for pancreatic cancer.
Purpose:
Phase II trial to study the effectiveness of combination chemotherapy in treating
patients with stage II or stage III pancreatic cancer that has not been surgically removed.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
|
Pancreatic Cancer |
Drug: dipyridamole Drug: fluorouracil Drug: leucovorin calcium Drug: mitomycin C |
Phase 2 |
Verified by
Southwest Oncology Group
January, 2013
Sponsored by: Southwest Oncology Group
Information provided by: Southwest Oncology Group
ClinicalTrials.gov identifier: NCT00003018
Study Type: Interventional
Study Design: Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States
William H. Isacoff, MD., Study Chair