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Combination Chemotherapy in Treating Children With Progressive Brain Tumors

Study:

Chemotherapy for Progressive Low Grade Astrocytoma in Children Less Than Ten Years Old

Rationale:

Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.

Purpose:

This randomized phase III trial is studying two different combination chemotherapy regimens and comparing how well they work in treating children with low-grade astrocytomas or other residual tumors of the brain.

Study Status: Completed

Recruiting:
n/a

Condition Intervention Phase
Brain Tumors
Central Nervous System Tumors
Drug: carboplatin
Drug: lomustine
Drug: procarbazine hydrochloride
Drug: thioguanine
Drug: vincristine sulfate
Phase 3

Verified by Children`s Oncology Group September, 2013

Sponsored by: Children`s Oncology Group
Information provided by: Children`s Oncology Group
ClinicalTrials.gov identifier: NCT00002944

Study Type: Interventional

Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States

Joann Ater, MD., Study Chair

This information is abridged to display results relevant only to Cleveland Clinic. To see complete record visit ClinicalTrials.gov
  Information obtained from ClinicalTrials.gov on
Link to the current ClinicalTrials.gov record.

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