Study:
NATIONAL WILMS TUMOR STUDY-5 -- TREATMENT OF RELAPSED PATIENTS
Rationale:
Drugs used in chemotherapy use different ways to stop tumor cells from dividing
so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor
cells. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor
to give higher doses of chemotherapy drugs and kill more tumor cells. It is not yet known
which therapy regimen is most effective for treating patients with kidney tumors.
Purpose:
Phase III trial to compare the effectiveness of chemotherapy with or without
radiation therapy, surgery, and/or peripheral stem cell or bone marrow transplantation in
treating young patients with kidney tumors.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
|
Kidney Cancer |
Biological: dactinomycin
Biological: filgrastim
Drug: carboplatin
Drug: cyclophosphamide
Drug: doxorubicin hydrochloride
Drug: etoposide
Drug: vincristine sulfate
Procedure: conventional surgery
Radiation: radiation therapy |
Phase 3 |
Verified by
Children`s Oncology Group
April, 2003
Sponsored by: Children`s Oncology Group
Information provided by: National Cancer Institute (NCI)
ClinicalTrials.gov identifier: NCT00002610
Study Type: Interventional
Study Design: Primary Purpose: Treatment
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States
Daniel M. Green, MD., Study Chair