Study:
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)
Rationale:
n/a
Purpose:
The purposes of this study are to assess rapidly innovative treatment methods in patients
with adult respiratory distress syndrome (ARDS) as well as those at risk of developing ARDS
and to create a network of interactive Critical Care Treatment Groups (CCTGs) to establish
and maintain the required infrastructure to perform multiple therapeutic trials that may
involve investigational drugs, approved agents not currently used for treatment of ARDS, or
treatments currently used but whose efficacy has not been well documented.
Study Status: Completed
Recruiting:
n/a
| Condition |
Intervention |
Phase |
Respiratory Distress Syndrome, Adult
Lung Diseases |
Procedure: Low Tidal Volume Ventilation
Procedure: Positive End-Expiratory Pressure
Drug: Lysofylline
Drug: Methylprednisolone
Drug: Ketoconazole
Procedure: Fluid Management
Procedure: Pulmonary Artery Catheter |
Phase 3 |
Verified by
National Heart, Lung, and Blood Institute (NHLBI)
August, 2006
Sponsored by: National Heart, Lung, and Blood Institute (NHLBI)
Information provided by: National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov identifier: NCT00000579
Study Type: Interventional
Study Design: Treatment, Placebo Control, Factorial Assignment
Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States
Edward Abraham, MD., Principal Investigator
Antonio Anzueto, MD., Principal Investigator
Roy Brower, MD., Principal Investigator
Alfred F. Connors, MD., Principal Investigator
Bennett P. deBoisblanc, MD., Principal Investigator
Bennett P. deBoisblanc, MD., Principal Investigator
Michael Donahoe, MD., Principal Investigator
Kalpalatha K. Guntupalli, MD., Principal Investigator
Robert D. Hite, MD., Principal Investigator
Robert D. Hite, MD., Principal Investigator
Rolf Hubmayr, MD., Principal Investigator
Neil MacIntyre, MD., Principal Investigator
Michael A. Matthay, MD., Principal Investigator
Alan Morris, MD., Principal Investigator
Michael J. Murray., Principal Investigator
James A. Russell, MD., Principal Investigator
Gregory A. Schmidt, MD, FCCP., Principal Investigator
David A. Schoenfeld, PhD., Principal Investigator
Jay S. Steingrub, MD, FCCP., Principal Investigator
Arthur Wheeler, MD., Principal Investigator
Herbert Wiedemann, MD., Principal Investigator