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40s

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1940's

Dr. Arta Green, team member, in front of machine used to isolate serotonin

Researcher Irvine Page, M.D., led several teams that made major discoveries regarding high blood pressure and its link to heart disease. Prior to coming to the Cleveland Clinic, Dr. Page's team discovered the association between renin and high blood pressure, and isolated the peptide angiotensin. In 1948, he and his team isolated the neurotransmitter serotonin, another key player in the cause of hypertension. Dr. Page would later be involved in another major breakthrough in this area during the next decade.


Dr. Hale

Donald E. Hale, M.D., is appointed chairman of The Cleveland Clinic's newly created Department of Anesthesiology in the Division of Surgery. The move marks the Clinic's early recognition of the importance of anesthesiology as a medical specialty.


Dr. Donald B. Effler, 1948

Dr. Effler in surgery, 1975.

In 1948, Donald B. Effler, M.D., is appointed head of the new Department of Thoracic Surgery, forerunner of the current Department of Thoracic and Cardiovascular Surgery.

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