- Novel tyramine linked hyaluronic acid (HA) derivatives in facial soft tissue reconstruction
Collaborator: Anthony Calabro, PhD. Dept of BME. CCF Lerner Institute
Current research is ongoing on the use of cross-linked HA as a long tern soft tissue replacement. This is presently funded by an RPC grant (# 7550, P.I. Daniel S. Alam, MD). Based on preliminary in vitro and in vivo data, the finding s of this project could represent a new paradigm in soft tissue reconstruction. We have submitted for a resident research award for long-term study and funding for our research resident who plans to dedicate his research year to this project. The initial data has been received with enormous interest from our national academy which published the abstract not only at the national meeting but because of it’s potential merit, included it into a newsletter sent to all of the members of the society of facial plastic surgeons nationally.
- Three-dimensional flow analysis of the nasal valve based on fine cut CT data.
Collaborator: Marc Goodin, PhD, Dept of BME. CCF Lerner Institute
With the utilization of flow dynamics models used presently in cardiology to study vessel flow, the section is pursuing the development of a model of flow limitation in nasal respiration. This will allow preoperative CT scans to predict and guide surgery for the improvement of nasal breathing. Compilation of data from presently existing CT scans from sinus patients has allowed the construction of a preliminary model.
- Novel surgical techniques
Application of novel techniques to longstanding surgical problems in facial plastic surgery:
- TMJ reconstruction in patients with composite reconstructions of the jaw: First reported use of alloderm based TMJ reconstruction with a fibula free flap bony construct.
- Midfacial Suspension for patients with long standing facial paralysis: Use of a minimally invasive novel suture suspension technique to rehabilitate patients with long standing facial paralysis and facial droop.
- Intranasal microplating for correction of cartilaginous nasal deformities: Novel approach to the management of posttraumatic nasal deformities
- Serratus/ Rib free flap reconstruction of head and neck defects: largest clinical series and report of the long term success of this flap in head and neck reconstruction