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Cleveland Clinic Geneticist Charis Eng MD PhD Elected to National Academy of Science's Institute of Medicine


Charis Eng, MD, PhD, Chair and founding Director of Cleveland Clinic’s Genomic Medicine Institute (GMI), is one of 65 new members elected to the Institute of Medicine (IOM) in 2010. This elite honor distinguishes those having made unparalleled contributions to health and biomedical science.

As the health arm of the National Academy of Sciences, the IOM functions as an authoritative body advising both decision makers and the public, with the underlying mission of improving human health. Members drawn from the highest levels of expertise in the country are selected to address the foremost healthcare issues and concerns facing the nation's health.

Dr. Eng is also the founding Director and attending clinical cancer geneticist of GMI's clinical component, the Center for Personalized Genetic Healthcare, and Professor and Vice Chair of the Department of Genetics at Case Western Reserve University School of Medicine.

Dr. Eng's seminal contributions in the area of clinical cancer genetics translational research – exemplified in part by her approach to RET testing and characterization of PTEN mutations, as well as her proactive involvement at the national level in guiding and advising on human genetics- and genomics-informed personalized healthcare – make her IOM membership a fitting distinction of professional achievement and commitment to service.

Dr. Eng has published 320 peer-reviewed original papers in such journals as the New England Journal of Medicine, Journal of the American Medical Association, Lancet, Nature Genetics, Nature, Cell, and Molecular Cell. She has completed a three-year term on the Board of Directors of the American Society of Human Genetics, as well as a two-year term as Chair of the Clinical Science Committee of the Personalized Medicine Coalition, and is currently serving a five-year term on the Board of Scientific Directors of the National Human Genome Research Institute.

Last year, Dr. Eng was appointed by Kathleen Sebelius to the U.S. Department of Health and Human Services' Secretary's Advisory Committee on Genetics, Health and Society, where she co-chairs their Task Force to examine whole genome sequencing for clinical application.

In addition to her numerous scientific and clinical achievements, Dr. Eng is also regarded for establishing a one-of-a-kind education program for training the next generation of clinical cancer geneticists, indicating her unmatched leadership in this emerging era of healthcare.

Within the IOM, Dr. Eng joins George Stark, PhD, a researcher in LRI’s Department of Molecular Genetics, as one of two Cleveland Clinic representatives in this national advisory capacity.

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Cleveland Clinic, located in Cleveland, Ohio, is a not-for-profit multispecialty academic medical center that integrates clinical and hospital care with research and education. It was founded in 1921 by four renowned physicians with a vision of providing outstanding patient care based upon the principles of cooperation, compassion and innovation. U.S. News & World Report consistently names Cleveland Clinic as one of the nation’s best hospitals in its annual “America’s Best Hospitals” survey. About 2,100 full-time salaried physicians and researchers and 11,000 nurses represent 120 medical specialties and subspecialties. In addition to its main campus, Cleveland Clinic operates nine community hospitals and 15 Family Health Centers in Northeast Ohio, Cleveland Clinic Florida, the Lou Ruvo Center for Brain Health in Las Vegas, Cleveland Clinic Canada, and opening in 2012, Cleveland Clinic Abu Dhabi. In 2009, there were more than 4.6 million visits throughout the Cleveland Clinic health system and 170,000 hospital admissions. Patients came for treatment from every state and from more than 100 countries. Visit us at

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